2009, discovery of a fresh phenotype for microorganisms in slender nanofluidic slits; and to start with detection of local protein structures along DNA utilizing strong-state nanopores

Our group studies bacterial mobile division which is aiming to constitute a ‘bottom up biology’ in artificial cells which will autonomously divide. Our major curiosity lies in cell division, chromatin composition, and spatial Management.

Multicolor imaging from the bacterial nucleoid and mobile division proteins with blue, orange, and in the vicinity of-infrared fluorescent proteins

2007, 1st genuine-time detection of strand exchange in homologous recombination by RecA; discovery of the low persistence duration of ends of microtubules; and settled the system of biosensing with carbon nanotubes

2015, discovery that condensin is actually a extremely adaptable protein framework; and initial detection of DNA knots using nanopores

The coiled-coil of your human Rad50 DNA repair service protein is made up of particular segments of greater versatility

MATLAB codes for data processing can be obtained at . Julia codes utilized for numerical simulation are available at .

Atomic force microscopy displays that vaccinia topoisomerase IB generates filaments on DNA inside of a cooperative style

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But carbon nanotubes have remained a investigate subject matter of sizeable fascination to a lot of. In fact, the outlook on working with carbon nanotubes to develop realistic products, cees dekker in regions for instance radio-frequency electronics, digital electronics and flexible electronics, remains bright.

‘The idea that There exists this kind of thing as being a starting, a giant bang, is already an interesting signpost to take into account that there was a creator. But additional usually, and on the basis of pure rationality, I also arrive at a Christian interpretation of actuality. An atheistic worldview can be a naturalistic worldview: essentially, there are actually only atoms and natural forces that we can measure.

2006, initially demonstration of molecular sorting in a lab on the chip working with biomotors; discovery of nanobubbles in solid-state nanopores; and 1st estimate of electrokinetic Electrical power conversion in a nanofluidic channel

Visualization of unstained DNA nanostructures with Highly developed in-focus transmission electron microscopy strategies

Reliable-condition nanopores have established to get a amazingly functional probe for solitary-molecule Examination of DNA. I will describe some of our recent findings – specifically DNA knots – as well as our endeavours to extend the abilities of reliable-condition nanopores even additional, within the direction of one-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.